Scientists and science writers discuss what it means to be alive in a world where life can be created, is under threat, and is still being discovered. Neil Shubin (Some Assembly Required: Decoding Four Billion Years of Life, from Ancient Fossils to DNA), Dr. Chanda Prescod-Weinstein (The Disordered Cosmos: A Journey into Dark Matter, Spacetime, and Dreams Deferred) and Carl Zimmer (Life’s Edge: The Search for What It Means to Be Alive) on the science, philosophy, and practice of drawing the line between life and everything else. An apple tree is alive—is an apple? Do extinct animals forecast the future of the Anthropocene? In an era when the definitions of life are being reconsidered, it is critically important that science education become more inclusive for all to be part of that discussion. Moderated by Bina Venkataraman, The Optimist’s Telescope.